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A three-day course designed to provide you with hands-on experience and
instruction with various fermentation systems. The program will acquaint
you with the techniques, methodologies, principles and applications of
aerobic bacterial and fungal fermentation and anaerobic bacterial fermentation.
The workshop provides an opportunity for participants to learn the principles of bacterial and fungal fermentation scale-up at the bench, as
well as recent advances and up-to-date applications of this methodology.
Lecture topics include an overview of fermentation, medium components and cell physiology, stoichiometry and kinetics, data analysis, oxygen consumption and transfer, computer-assisted control and monitoring, quality control and assurance,process scaleup, safety, and inoculation and sampling.
Laboratory sessions include assembly and disassembly of benchtop fermentors (2-5 liter) from four different vendors, sterilization procedures, preparation of inoculum and inoculation, process sampling, measurement of optical density and glucose levels, process control, and harvesting techniques.
This year the workshop has been streamlined into a three-day format. The workshop laboratory will tale place in a newly-renovated learning facility located within the University of Maryland Bioprocess Scaleup Facility
(BSF) on the College Park campus. The BSF houses bioprocessing equipment for process development and optimization ranging from 1 L to 350 L. All workshop participants will examine and test large scale fermentation equipment while they perform their own experiments on benchtop units provided by four vendors. The three-day format is fast-paced but plenty of time has been allocated for discussions with the workshop faculty. |
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