红霉素

细履平沙

红霉素：
产生菌：Streptomyces erythreus
结构：Erythromycin is a polyhydroxylactone that contains two sugars. The aglycone portion of the molecule, erythranolide, is a 14-membered lactone ring. An amino sugar, D-desosamine, is attached through a b-glycosidic linkage to the C-5 position of the lactone ring. The tertiary amine of desosamine confers a basic character to erythromycin (pK 8.8). Through this group, a number of acid salts of the antibiotic have been prepared. A second sugar, L-cladinose, which is unique to erythromycin, is attached via a b-glycosidic linkage to the C-3 position of the lactone ring. The fermentation process that produces commercial grade erythromycin is not entirely selective. It results in the production of small quantities of erythromycin B (EB), C(EC), D(ED), E(EE) and F(EF), in addition to EA, which is the major component.EB, EC and EE are the most important impurities found in commercial samples of erythromycin.

chongqingydr

红霉素发酵是一个多组分，根据资料显示在发酵液和成品中涉及影响组分的成分有A、B、C、D、E、F六个组分，另外还有NdMeEA，AEA，PsEAEN，EAEN等，版主已经列出了7个，能不能将其余的三个也给出，我查了些资料一直没有找到。谢谢

冬虫夏草

[quote]引用第1楼chongqingydr于2007-10-20 17:31发表的“”:
红霉素发酵是一个多组分，根据资料显示在发酵液和成品中涉及影响组分的成分有A、B、C、D、E、F六个组分，另外还有NdMeEA，AEA，PsEAEN，EAEN等

EP上有，很全的。